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Columns and cartridges for gas, ion, HPLC, low-pressure LC, and flash chromatography; includes pre-packed and open columns, packing, guard columns and accessories, and other supplies for flash chromatography.
YMC-Pack Pro C18 columns start with a tightly controlled highly purified silica gel followed by a high-coverage C18 bonding and finished with a unique endcapping procedure utilizing Lewis acid/Lewis base chemistry Together these features provide unequaled separations with sharp and symmetrical peaks for all types of organic molecules especially basic pharmaceuticals and chelating compounds
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YMC-Pack Pro C18 columns start with a tightly controlled highly purified silica gel followed by a high-coverage C18 bonding and finished with a unique endcapping procedure utilizing Lewis acid/Lewis base chemistry Together these features provide unequaled separations with sharp and symmetrical peaks for all types of organic molecules especially basic pharmaceuticals and chelating compounds
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YMC-Triart phases are based on organic/inorganic hybrid particles that combine the high mechanical stability and efficiency of a silica-based packing material with the robust chemical stability of a polymer-based packing material This versatile resin is produced using tightly controlled particle formation technology adapted from micro-reactor technology The resulting uniform particle and pore size distributions as well as the smooth surface greatly contribute to excellent peak shape and separation reproducibility In addition YMC-Triart materials are highly resilient and robust when used at extreme pH elevated temperature and high pressure
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The high-purity silica found in YMC-Pack SIL columns provides virtually complete sample recovery The absence of silica impurities reduces non-specific sample adsorption and the totally porous nature of the silica provides high sample loading The elevated chemical purity of YMC silica results in a particle structure exhibiting high mechanical strength YMC-Pack SIL is suitable for separation of fat-soluble compounds using non-polar mobile phases as well as the separation of positional isomers that are difficult to separate in reversed-phase mode SIL-06 (60 pore size) has greater adsorption properties than SIL (120 pore size) due to its larger surface area and is generally useful for separating natural products with low molecular weight
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YMC-Pack ODS-AL is a non-endcapped high carbon load monomeric C18 phase It exhibits different selectivity from conventional ODS columns due to the use of not only hydrophobic interaction but also secondary interactions caused by silanol groups YMC-Pack ODS-AL is intended for use only in those situations where residual silanol activity is beneficial to the separation
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YMC-Pack ODS-AQ is a unique reversed-phase material with both a hydrophobic high carbon loading and a relatively hydrophilic surface Because of the hydrophilic surface ODS-AQ can be wetted with polar eluents It provides chromatographers reproducible retention and excellent peak shape in highly aqueous mobile phases including 100% water This is due to the C18 ligands on ODS-AQ actually being lifted from the surface by the action of the eluents penetrating the silica pores Selectivity on YMC-Pack ODS-AQ can be subtly different from that seen on conventional ODS columns Differences in selectivity are most often encountered when analyzing mixtures of relatively polar compounds Typically longer retention and greater resolution are observed with ODS-AQ Available in both 120 and 200 pore sizes YMC-Pack ODS-AQ is well-suited for analysis and purification of peptides and other biomolecules
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YMC-Pack C4 is ideal for analyzing mixtures with a wide range of component polarity This is due to the C4 bonded phase exhibiting shorter analysis time while still maintaining high resolution when compared to longer-chain bonded chemistries YMC-Pack C4 (Butyl) columns are available with three pore sizes to accommodate optimum separations of virtually any molecular-weight compound The 120 phase is used extensively with non-polar peptides which are too strongly retained on C8 and C18 The 200 and 300 phase columns effectively resolve many classes of proteins and biopolymers The wide pore butyl chemistry allows minimal distortion of tertiary conformation for large biomolecules and results in samples that are pure concentrated and high in biological activity
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YMC-Triart phases are based on organic/inorganic hybrid particles that combine the high mechanical stability and efficiency of a silica-based packing material with the robust chemical stability of a polymer-based packing material This versatile resin is produced using tightly controlled particle formation technology adapted from micro-reactor technology The resulting uniform particle and pore size distributions as well as the smooth surface greatly contribute to excellent peak shape and separation reproducibility In addition YMC-Triart materials are highly resilient and robust when used at extreme pH elevated temperature and high pressure
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YMC s CHIRAL ART series features polysaccharide-derived chiral stationary phases (CSPs) based on amylose and cellulose tris-carbamate derivatives available in both coated and immobilized formats These columns provide exceptional stereoselectivity durability and solvent versatility supporting normal-phase reversed-phase and supercritical fluid chromatography (SFC) modes
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YMC-SEC MAB is a silica based size exclusion chromatography column specifically designed for antibody separations Optimized base material design and surface modification provide superior separation of antibody monomers and their aggregates/fragments with very low nonspecific adsorption This is ideal for the quality control assessment of antibody drugs YMC-SEC MAB exhibits excellent resolution and peak shape over a wide molecular weight range of 10 kDa to 700 kDa
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YMC-Pack Diol-NP is a versatile alternative to silica for normal phase separations and provides much better reproducibility when compared to bare silica material It shows typical normal phase retention behavior when used with low-polarity mobile phases due to hydroxyl groups on the surface of the stationary phase acting as polar groups YMC-Pack Diol-NP can also be used in HILIC-mode with organic/water mobile phases
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YMC-Pack ODS-AM is produced with specific emphasis on lot-to-lot reproducibility of the packing material Strict manufacturing control is performed on all aspects of quality including physical properties of the silica base gel as well as surface modifying processes ensuring exceptional reproducibility
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YMC-Pack TMS columns are bonded with trimethylmonochlorosilane to create a phase with intermediate polarity This makes for a versatile stationary phase that is useful for analysis of extremely hydrophobic compounds using conventional reversed-phase solvents or highly polar compounds using high aqueous solvents The unique chemistry of this packing material is also well-suited for the analysis of multifunctional compounds Selectivity characteristics of a C1 bonded phase can be unique and samples must be evaluated to determine the applicability of the phase
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YMC-Pack PVA-Sil is prepared from a 5 m 120 silica support which is bonded with a monomolecular polymer coating of vinyl alcohol The polymerized PVA completely covers both external and internal surfaces of the silica support protecting it against aggressive high pH buffers and solvents
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YMC-Pack PVA-Sil is prepared from a 5 m 120 silica support which is bonded with a monomolecular polymer coating of vinyl alcohol The polymerized PVA completely covers both external and internal surfaces of the silica support protecting it against aggressive high pH buffers and solvents
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